| Drug Name | ||
| Eligible | Study sites | More information |
| ADI-001 (not yet named) | ||
| Adults with IIM | Buffalo, NY [Enrolling by invitation] | More details » Adicet Therapeutics 716-845-3057 NCT06375993 |
Anifrolumab (JASMINE) | ||
| Ages 18-75 with DM or PM | 217 sites worldwide | More details » AstraZeneca 877-240-9479 NCT06455449 |
| AP01 (not yet named) | ||
| Adults with myositis and progressive ILD | 150+ sites worldwide [Not currently recruiting] | More details » Avalyn Pharma [email protected] NCT06329401 |
| AZD0120 (AURORA) | ||
| Ages 18-75 with IIM | 18 sites worldwide | More details » AstraZeneca 877-240-9479 NCT07295847 |
| AZD5492 | ||
| Ages 18-70 with PM or DM | 37 locations worldwide | More details » AstraZeneca 877-240-9479 NCT06916806 |
CABA-201 (CAR T cell therapy) | ||
| Ages 6-75 with DM, ASyS, IMNM | 25 sites in the US and UK | More details » Cabaletta Bio NCT06154252 |
CD-19-Targeted (CAR T cell therapy) | ||
| Adults with refractory DM, PM, IMNM | 54 sites in US and Europe [Not currently recruiting] | More details » Bristol Myers Squibb 855-907-3286 NCT05869955 |
Dazukibart | ||
| Adults with active DM or PM | 128 sites worldwide | More details » Pfizer 800-718-1021 NCT05895786 |
| Descartes-08 | ||
| Adults with DM or ASyS | 4 sites in US | More details » Cartesian Therapeutics [email protected] 617-231-8085 NCT07391605 |
Efgartigimod (ALKIVIA) | ||
| Adults with IIM | [Study completed] | More details » argenx 857-350-4834 NCT05523167 |
| Empasiprubart (Empacific) | ||
| Adults with DM | (currently not recruiting) | More details » argenx 857-350-4834 NCT06284954 |
| Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM) | ||
| Adults with DM, JDM | NIH, Bethesda, MD | More details » [email protected] 301-496-6664 NCT07111065 |
| IVIG The MIGHT Trial – An Exploratory Clinical Trial of IVIG in Anti-HMGCR Immune Mediated Necrotizing Myopathy | ||
| Adults age 16 or older with HMGCR autoantibody IMNM | 5 sites in US | More details » Hannah E Howell, MS [email protected] 205-996-6552 NCT06599697 |
Nerandomilast (VERANDA) | ||
| Adults with IIM | 141 sites worldwide | More details » Boehringer Ingelheim [email protected] 1-800-243-0127 NCT07789015 |
| Nipocalimab (SPIREA) | ||
| Adults with IIM | [Currently not recruiting] | More details » J&J Innovative Medicine 844-434-4210 NCT05379634 |
NKX019 (allogeneic CAR NK cells targeting CD19) | ||
| Ages 18-65 with DM, IMNM, or ASyS | 18 sites in US | More details » Nkarta, Inc. [email protected] NCT06733935 |
| Pozelimab and Cemdisiran | ||
| Ages 45-75 with sIBM | 2 sites in Austin, TX | More details » Austin Neuromuscular Center Yessar Hussain, MD [email protected] 512-930-0140 NCT06479863 |
Rapcabtagene Autoleucel (CAR T cell therapy) | ||
| Adults with DM, NM, ASyS | 68 sites worldwide [Currently not recruiting] | More details » Novartis 1-888-669-6682 NCT06665256 |
| RAY121 (RAINBOW Trial) | ||
| Ages 18-75 with DM or IMNM | 77 sites worldwide | More details » Chugai Pharmaceuticals Co., Ltd [email protected] NCT06371417 |
| Sirolimus | ||
| Adults with inclusion body myositis (IBM) | [Currently not recruiting] | More details » 913-945-9926 NCT04789070 |
| Ublituximab in Autoantibody Positive Immune Mediated Necrotizing Myopathy (SUMMIT) | ||
| Adults with IMNM | 8 Study sites in US | More details » National Institute of Allergy and Infectious Diseases (NIAID) NCT07103746 |