There is good news for IBM patients who want to participate in the arimoclomol clinical trial. Pharmaceutical company Orphazyme recently announced the addition of several new clinical sites for the trial. This makes a total of five places in the US where eligible patients can participate.

Arimoclomol is an experimental drug that is believed to stimulate normal protein repair in the cell. Damaged proteins, called aggregates, are thought to play a role in IBM. Early clinical trials with this compound have shown promise in patients with IBM, and many TMA members have been eagerly awaiting the start of this larger, multi-center trial.

The following sites in the US  are currently accepting participants:

  • University of Colorado School of Medicine, Aurora, Colorado
  • Brigham and Women’s Hospital, Boston, Massachusetts
  • The Ohio State University, Columbus, Ohio
  • Nerve and Muscle Center of Texas, Houston, Texas
  • University of Kansas, Kansas City, Kansas (We understand that this site is already full, however.)

University College of London in the UK is also accepting participants.

Please see ClinicalTrials.gov for inclusion criteria and contact information for site coordinators.  More sites are expected to come online soon, and TMA will update members when they do.

 

14 comments on “Arimoclomol clinical trial for IBM”

  1. 1
    richard carlsen on October 8, 2018

    I am looking for a trial in salt lake city

    1. 2
      Linda Kobert on October 8, 2018

      Richard, there are four additional sites expected. Not sure there will be one in Salt Lake City, but there may be one you can travel to.

  2. 3
    Gerry Hongell on October 9, 2018

    ANY in Canada?

    1. 4
      Linda Kobert on October 10, 2018

      Gerry, I’m afraid there are no sites for this study in Canada, at least not yet.

  3. 5
    Selena Antonic on October 12, 2018

    Selena Antonic
    I am looking for trial anywhere in Canada, although
    I live in Toronto.

    1. 6
      Linda Kobert on October 12, 2018

      Selena, I’m afraid there are no sites for this trial in Canada, at least not yet. Rochester, NY may be your best bet.

  4. 7
    JoAnne Oliver on October 14, 2018

    Is Austin, Texas slated for a trial?

    1. 8
      Linda Kobert on October 14, 2018

      JoAnne, here is the info for the Nerve and Muscle Center of Texas in Houston. This is probably the closest. Contact: Zinah Rasheed, BS 713-795-0033 ext 16 ataher@aol.com

  5. 9
    Jack Ferko on October 15, 2018

    Is there any plans for trials in Las Vegas, Nevada?

    1. 10
      Linda Kobert on October 17, 2018

      Jack, TMA has not been informed of all the planned sites for this trial. The company, Orphazyme, expects to have all additional sites up and running by the end of the year at the latest. All new recruiting sites and their contact info will be displayed here when they come online: https://www.clinicaltrials.gov/ct2/show/NCT02753530

  6. 11
    Jack Luster on October 15, 2018

    Is the UCI clinical trial slated to start any time soon?

    1. 12
      Linda Kobert on October 17, 2018

      It is our understanding that, yes, the UC Irvine site should be recruiting soon.

  7. 13
    Umberto Carosi on October 15, 2018

    Would you know the eligibility requirements to get accepted?

    1. 14
      Linda Kobert on October 17, 2018

      Umberto, you can find the eligibility criteria here: https://www.clinicaltrials.gov/ct2/show/NCT02753530

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